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發表於 2020-2-4 13:04:55
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本帖最後由 wongwingkin 於 2020-2-4 13:06 編輯
directcom 發表於 2020-2-4 12:46
1月13號肺炎首次傳出國外，嗰陣全國只得武漢有疫情，到1月20號至話傳到廣東，所以至畀人笑係愛國肺炎。搞清楚啲時序，唔好因為港大喺深圳有間醫院就當佢掌握到數據。
人傳人吾洗傳到外國先當有的，吾早兩个星期講，早一个都会少好多人中招。有興趣可以睇吓(深圳一家五口一月初人傳人个案):
https://www.thelancet.吾com/journals/lancet/article/PIIS0140-6736(20)30154-9/fulltext
Lancet. 2020 Jan 24. pii: S0140-6736(20)30154-9. doi: 10.1016/S0140-6736(20)30154-9. [Epub ahead of print]
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.
Chan JF1, Yuan S2, Kok KH2, To KK1, Chu H2, Yang J3, Xing F3, Liu J3, Yip CC2, Poon RW2, Tsoi HW2, Lo SK3, Chan KH2, Poon VK2, Chan WM2, Ip JD2, Cai JP2, Cheng VC2, Chen H1, Hui CK4, Yuen KY5.
Author information
Abstract
BACKGROUND:
An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients were geographically linked with a local wet market as a potential source. No data on person-to-person or nosocomial transmission have been published to date.
METHODS:
In this study, we report the epidemiological, clinical, laboratory, radiological, and microbiological findings of five patients in a family cluster who presented with unexplained pneumonia after returning to Shenzhen, Guangdong province, China, after a visit to Wuhan, and an additional family member who did not travel to Wuhan. Phylogenetic analysis of genetic sequences from these patients were done.
FINDINGS:
From Jan 10, 2020, we enrolled a family of six patients who travelled to Wuhan from Shenzhen between Dec 29, 2019 and Jan 4, 2020. Of six family members who travelled to Wuhan, five were identified as infected with the novel coronavirus. Additionally, one family member, who did not travel to Wuhan, became infected with the virus after several days of contact with four of the family members. None of the family members had contacts with Wuhan markets or animals, although two had visited a Wuhan hospital. Five family members (aged 36-66 years) presented with fever, upper or lower respiratory tract symptoms, or diarrhoea, or a combination of these 3-6 days after exposure. They presented to our hospital (The University of Hong Kong-Shenzhen Hospital, Shenzhen) 6-10 days after symptom onset. They and one asymptomatic child (aged 10 years) had radiological ground-glass lung opacities. Older patients (aged >60 years) had more systemic symptoms, extensive radiological ground-glass lung changes, lymphopenia, thrombocytopenia, and increased C-reactive protein and lactate dehydrogenase levels. The nasopharyngeal or throat swabs of these six patients were negative for known respiratory microbes by point-of-care multiplex RT-PCR, but five patients (four adults and the child) were RT-PCR positive for genes encoding the internal RNA-dependent RNA polymerase and surface Spike protein of this novel coronavirus, which were confirmed by Sanger sequencing. Phylogenetic analysis of these five patients' RT-PCR amplicons and two full genomes by next-generation sequencing showed that this is a novel coronavirus, which is closest to the bat severe acute respiatory syndr
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樓主: wongwingkin
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發表於 2020-2-4 12:37:16
